SOY ISOFLAVONE EXTRACT 40%, 120 capsules, 250 mg, HPLC Tested
Each capsule contains 33 mg Genistein and 76 mg Daidzein.
SOY ISOFLAVONES have been in the news recently for their known help in lowering cholesterol and reducing the risk of heart disease.
This supplement is also important for prostate health.
The main constituents in soy that are helpful are genistein and daidzein.
These are NOT "phytoestrogens" as many so-called experts will allege as there is no estrogen, or testosterone, progesterone, DHEA, melatonin in any plant.
Studies on prostate health and isoflavones have been published in journals such as Prostate, Anticancer Research, Journal of Endoctrinology and many others.
Soy Isoflavones also Reduces Menopause Symptoms, read more below.
Genistein
Genistein is a phytochemical found in soybeans.[38] Soybeans contain a variety of phytochemicals, and in particular they are the only source with nutritionally significant amounts of one type of phytochemical called isoflavones.
Foods that contain large amounts of soy are tofu, soy milk, and miso.
In soy consuming populations, the concentrations of genistein average 0.28 µM, which is ten-fold higher than that seen in non-soy consuming populations.[39] Much interest has been shown recently in genistein as a chemopreventive agent in prostate cancer.
Both epidemiological and migrant studies have demonstrated a correlation between increased isoflavone levels in the serum and urine of Asian men with decreased levels of prostate cancer.[40] Also, in a cross-national study for which data was available from 42 countries, soy products were identified as having a significant protective effect against prostate cancer.[41]
Genistein is a potent inhibitor of protein-tyrosine kinase and topoisomerase II, enzymes which are crucial to cellular proliferation.
Genistein is also an inhibitor of angiogenesis and several steroid metabolizing enzymes, such as aromatase and 5 alpha-reductase.[42] A NCI-sponsored placebo-controlled clinical trial, Phase I Randomized Study of Genistein in Patients with Stage III or IV Prostate Cancer, has been underway since December 1999 to determine the safety and pharmacokinetics of genistein
SupplementSpot's Soy Isoflavones have what you need, not only for prostate health, but to also to prevent high cholesterol and heart disease.
Soy Isoflavones Reduce Menopause Symptoms
March 21, 2002 -- Journal of Obstetrics and Gynecology -- Healthnotes Newswire
Postmenopausal women who take a daily supplement containing soy isoflavones may experience fewer symptoms associated with menopause, according to a new study in Obstetrics and Gynecology.1
Isoflavones are a group of compounds found in certain beans and grains that have mild estrogen-like activity (thus, are commonly referred to as "phytoestrogens").
Research suggests that the soy's phytoestrogenic activity is due to two isoflavones in particular, daidzein and genistein.2
This four-month controlled trial examined 80 postmenopausal women between 45 and 55 years old, who were assigned to receive either 100 mg of soy isoflavones per day or placebo.
Frequency and severity of 11 different menopausal symptoms were measured by questionnaire before and after treatment.
Blood cholesterol and sugar levels, blood pressure, body mass index (BMI; a measure of obesity) and reproductive hormones were measured at the same intervals.
The results showed a significant decrease in menopausal symptoms from the beginning to the end of the study in women taking soy isoflavones.
In addition, menopausal symptom scores in women taking soy isoflavones were 40% lower (indicating less severe symptoms) than in those taking a placebo, a statistically significant difference.
No significant differences were found in blood sugar, blood pressure or BMI between the two groups of women.
In women taking soy isoflavones, blood levels of estradiol (a type of estrogen) doubled, whereas estradiol levels did not change in women taking the placebo.
However, as isoflavone treatment did not increase the thickness of the uterine lining, this treatment does not appear to increase the risk of uterine cancer.
Compared with the placebo group, the soy group had a significant reduction in total cholesterol and LDL (“bad”) cholesterol, suggesting that soy has heart-health benefits as well.
Other studies have demonstrated that daily consumption of soy decreases the risk of developing cardiovascular disease, including stroke and heart attack.3 However, it is not clear whether the cardiovascular benefits of soy are due to the isoflavones or to other components of soy.
Symptoms of menopause may include hot flashes, insomnia, nervousness, joint pain, headache, or heart palpitations.
Estrogen replacement therapy (ERT) is used conventionally to treat these symptoms, but may increase the risk of developing uterine and breast cancer.
The authors of the new study suggest that taking a daily supplement of soy isoflavones may be a safe and effective treatment to control the symptoms of menopause, without increasing cancer risk.
-- Darin Ingels, N.D.
References:
Han KK, Soares JM Jr, Haidar MA, et al.
Benefits of Soy Isoflavone Therapeutic Regimen on Menopausal Symptoms.
Obstet Gynecol 2002;99:389–94.
Wei H, Brown R, Cai Q, et al.
Antioxidant and antipromotional effects of the soybean isoflavone genistein.
Proc Soc Exp Biol Med 1995;208:124–9.
Sirtori CR.
Risks and benefits of soy phytoestrogens in cardiovascular diseases, cancer, climacteric symptoms and osteoporosis.
Drug Saf 2001;24:665–82.
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