Glutamine Peptides
Glutamine Peptides Glutamine is technically a semi-essential amino acid because there are times when it cannot be manufactured by the body. When the body is subjected to such metabolic stress situations as trauma, including surgeries, cancer, sepsis and burns, Glutamine becomes an essential amino acid. Officially, however, it is classified as a non-essential amino acid. Glutamine is usually advertized in the most natural L form. D-glutamine has no biological activity.
Glutamine has a unique structure with each molecule containing two atoms of nitrogen instead of one -- an aspect that enables it to clear ammonia from the tisssues, especially the brain. Glutamine is also an important carrier of urinary ammonia, which is broken down in the kidneys by glutaminase.
Glutamine is the most abundant amino acid in the blood and cerebrospinal fluid, and is the only amino acid that easily passes the blood-brain barrier. In the brain, glutamine converts to glutamic acid, which is essential for cerebral function. While glutamic acid is probably the active form in the brain, it is glutamine that is more efficiently transported throughout the rest of the body, ultimately causing a higher glutamic acid concentration needed in the brain.
Glutamine is the dominant amino acid in muscle tissue, comprising some 61% of the total amino acid pool: a factor commonly utilized by body builders to help reduce muscle deterioration during workouts. Because of its unique structure, containing two nitrogen side chains, glutamine becomes the primary transporter of nitrogen into muscle cells where it is synthesized for growth. However, the demand for glutamine by the intestines, as well as by such cells as lymphocytes, appears to be much greater than what can be supplied by skeletal muscles, which are the major storage tissue for L-glutamine. Glutamine is also the preferred respiratory fuel for enterocytes, colonocytes and lymphocytes.
Although glutamine has some great benefits, there are some who think the peptide-bonded form might actually work better. Much of the ingested free form L-glutamine does not make it into the blood stream or muscle tissue. It is estimated that anywhere from 50-85% is immediately used by the intestines, liver, and the immune system. This is what many scientists refer to as the “glutamine paradox": a problem which is apparently solved by using the glutamine peptide bonded chain.
Glutamine peptide is also much more stable in solution, higher temperatures, and low PH than free form L-glutamine since it tends to break down to ammonia and glutamic acid rather quickly in solution. The digestive tract has peptide transport systems that allow peptides to be better absorbed and utilized. Therefore, the peptide bonded form is thought to enhance the availability of the glutamine in the bloodstream, making it more readily available to muscle tissue.
Glutamine peptides are bonded to other amino acids with peptide bonds, making them more stable and better utilized by the body. A product that combines both ensures better uptake, absorption, and stability and allows for better transport into the blood stream and muscle tissue.
Benefits
There are several benefits attributed to glutamine that science is discovering. Among the most important are its impact on the immune system and its ability to reduce alcohol and sugar craving severely. It is also proving to be a valuable supplement in protecting against the side effects of cancer therapies, impotence, fatigue, epilepsy, senility, and mental problems including depression and schizophrenia and mental retardation.
Glutamine is often a recommended treatment to improve mood, focus, concentration, memory, and to increase energy. It is often deficient in those with chronic yeast overgrowth: a depletion which is partially responsible for the “fuzzy thinking” described by these individuals.
Glutamine has been particularly successful in treating those with irritable bowel syndromes -- ulcerative colitis, celiac disease, ulcers, and leaky gut. Glutamine plays a key role in the metabolism, structure, and function of the entire gastrointestinal tract. It is the primary energy source for the cells that line the intestines and is essential in keeping the digestive tract healthy and functioning properly.
In Europe, glutamine is routinely given to hospital patients to increase their healing process and immune systems while reducing their hospital stays. In North America, glutamine peptides in TPN solutions have proven beneficial in patients with varying forms of catabolic stress including cancer, transplantation, intensive-care, surgical and the immune-suppressed. Oral glutamine supplementation has also been successfully used in very low birth-weight infants.
How should I use GLUTA-PEP™?
As a dietary supplement, take 4 capsules 1-2 times per day. On training days, take 4 capsules directly after workout. One bottle contains 120 capsules.
Do I need a prescription to use GLUTA-PEP™?
No you don't. Because GLUTA-PEP™ is an all natural nutritional supplement containing only the finest nutritional ingredients, there is no need to obtain a prescription.
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